A shooting at a family planning clinic in Colorado Springs has left two civilians and a police officer dead, with the suspected gunman under arrest.
Nine other people were injured during the standoff at the Planned Parenthood clinic, which lasted five hours before the suspect surrendered.
A number of people were trapped inside the building as shots were exchanged.
The motive remains unclear. The Planned Parenthood group has drawn anti-abortion protests in the past.
Colorado Springs Police Department identified the suspect as Robert Lewis Dear, from North Carolina.
"I want to convey to the loved ones of the victims, this is a terrible, terrible tragedy that occurred here in Colorado Springs today," Mayor John Suthers told a news conference.
"Obviously, we lost two civilian victims. We mourn the loss of a very brave police officer."
The dead policeman was named as Garrett Swasey, 44, who was married with two children.
President Barack Obama said: "We have to do something about the easy accessibility of weapons of war on our streets to people who have no business wielding them. Enough is enough."
He has previously expressed his frustration after other fatal shootings about not being able to do more on gun control.